Article
Stromelysin gene promoter polymorphism and common carotid geometry in diabetic subjects.
International angiology : a journal of the International Union of Angiology - 1 Oct 2008
Irace C, Cortese C, Migale M, Liberatoscioli L, Mannucci L, Federici G, Gnasso A
Abstract excerpt
AIM: Stromelysin (MMP3), through its action on collagen and other matrix metalloproteinases, influences arterial wall remodeling. In healthy subjects, the 5A/6A polymorphism located in the promoter of the MMP3 gene is associated with common carotid remodeling, 6A/6A subjects having increased arte...
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