Article
Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives.
Circulation - 10 Feb 2004
Planat-Benard Valérie, Silvestre Jean-Sébastien, Cousin Béatrice, André Mireille, Nibbelink Maryse, Tamarat Radia, Clergue Michel, Manneville Carole, Saillan-Barreau Corinne, Duriez Micheline, Tedgui Alain, Levy Bernard, Pénicaud Luc, Casteilla Louis
Abstract excerpt
BACKGROUND: Adipose tissue development and remodeling are closely associated with the growth of vascular network. We hypothesized that adipose tissue may contain progenitor cells with angiogenic potential and that therapy based on adipose tissue-derived progenitor cells administration may constitute a promising cell therapy in patients with ischemic disease. METHODS AND RESULTS: In mice, cultured stromal-vascular...
Topics
- Adipocytes
- Adipose Tissue
- Animals
- Biomarkers
- Cell Differentiation
- Cell Lineage
- Cells, Cultured
- Endothelium, Vascular
- Humans
- Ischemia
