Article
Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries.
Genetics - 1 Dec 2008
Chiang Charleston W K, Derti Adnan, Schwartz Daniel, Chou Michael F, Hirschhorn Joel N, Wu C-Ting
Abstract excerpt
Ultraconserved elements (UCEs) are sequences that are identical between reference genomes of distantly related species. As they are under negative selection and enriched near or in specific classes of genes, one explanation for their ultraconservation may be their involvement in important functio...
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