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Article

Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans.

BMC microbiology - 24 Oct 2008

Thewes Sascha, Moran Gary P, Magee Beatrice B, Schaller Martin, Sullivan Derek J, Hube Bernhard

Abstract excerpt

BACKGROUND: Invasion of host tissue by the human fungal pathogen Candida albicans is an important step during the development of candidosis. However, not all C. albicans strains possess the same invasive and virulence properties. For example, the two clinical isolates SC5314 and ATCC10231 differ in their ability to invade host tissue and cause experimental infections. Strain SC5314 is invasive whereas strain...

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PMID: 18950481
DOI: 10.1186/1471-2180-8-187
PMCID: PMC2579918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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