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Article

A mouse translocation associated with Caspr5-2 disruption and perinatal lethality.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2000

Weichenhan Dieter, Traut Walther, Göngrich Christina, Himmelbauer Heinz, Busch Lüder, Monyer Hannah, Winking Heinz

Abstract excerpt

We have previously described the paralogous mouse genes Caspr5-1, -2, and -3 of the neurexin gene family. Here we present the cytogenetic and molecular mapping of a null mutation of Caspr5-2 which was caused by reciprocal translocation between chromosomes 1 and 8 with breakpoints at bands 1E2.1 and 8B2.1, respectively. The translocation disrupts Caspr5-2 between exons 1 and 2 and causes stillbirth or early...

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Share to Cell Adhesion Molecules, Neuronal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Artificial, Bacterial

Share to Crosses, Genetic

Share to Genes, Lethal

Share to In Situ Hybridization, Fluorescence

Share to Translocation, Genetic

Source

Identifiers

PMID: 18949514
DOI: 10.1007/s00335-008-9148-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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