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Article

Prevention of cadmium accumulation in retinal pigment epithelium with manganese and zinc.

Experimental eye research - 1 Dec 2008

Satarug Soisungwan, Kikuchi Mihoko, Wisedpanichkij Raewadee, Li Bin, Takeda Kazuhisa, Na-Bangchang Kesara, Moore Michael R, Hirayama Kenji, Shibahara Shigeki

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the elderly. Risk factors include old age, female gender, obesity, smoking, low dietary intakes of antioxidants and increased exposure to the toxic metal cadmium (Cd(2+)). Supplementation with high-dose zinc (80 mg) provides some protection, but the mechanism(s) underlying such protection has not been fully elucidated. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18948096
DOI: 10.1016/j.exer.2008.09.014

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RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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