Article
Polymorphisms of survivin and its protein expression are associated with colorectal cancer susceptibility in Chinese population.
DNA and cell biology - 1 May 2013
Li Xia-Bin, Li Shi-Ning, Yang Zhi-Hui, Cao Ling, Duan Fang-Lei, Sun Xing-Wang
Abstract excerpt
To investigate the association of survivin -31G/C, -141G/C, and -241T/C polymorphisms with colorectal cancer (CRC) susceptibility and explore the mechanisms of the survivin polymorphism in CRC development. A case-control study was conducted of 275 CRC cases and 270 healthy controls. Polymorphisms of survivin -31G/C, -141G/C, and -241T/C were genotyped by polymerase chain reaction-restriction fragment length...
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