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Article

Association between haplotypes of manganese superoxide dismutase (SOD2), smoking, and lung cancer risk.

Free radical biology & medicine - 1 Jan 2009

Gallagher Carla J, Ahn Kwangmi, Knipe Ashley L, Dyer Anne-Marie, Richie John P, Lazarus Philip, Muscat Joshua E

Abstract excerpt

Tobacco smoke contains high concentrations of reactive oxygen species (ROS) that can damage DNA, proteins, and lipids. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals into hydrogen peroxide and protects against oxidative stress in lung tissues. Three tagSNPs were identified in one block of high linkage disequilibrium that spans the entire SOD2 gene and 5-kb promoter region....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18930810
DOI: 10.1016/j.freeradbiomed.2008.09.018
PMCID: PMC2630476

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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