Article
Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypes.
Psychophysiology - 1 Nov 2002
Ross Randal G, Olincy Ann, Mikulich Susan K, Radant Allen D, Harris Josette G, Waldo Merilyne, Compagnon Nina, Heinlein Shari, Leonard Sherry, Zerbe Gary O, Adler Lawrence, Freedman Robert
Abstract excerpt
Abnormalities during a smooth pursuit eye movement task (SPEM) are common in schizophrenic patients and their relatives. This study assessed various components of SPEM performance in first-degree unaffected relatives of schizophrenic patients. One hundred individuals with schizophrenia, 137 unaffected first-degree relatives, and 69 normal controls completed a 16.7 degrees/s SPEM task. Smooth pursuit gain,...
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