Article
Visual fixation and smooth pursuit eye movement abnormalities in patients with schizophrenia and their relatives.
The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 1995
Amador X F, Malaspina D, Sackeim H A, Coleman E A, Kaufmann C A, Hasan A, Gorman J M
Abstract excerpt
Increasing evidence suggests that smooth pursuit eye movement (SPEM) dysfunction may serve as an endophenotype or genetic marker of schizophrenia. The authors tested SPEM and visual fixation (VF) in 31 patients with schizophrenia, 33 of their first-degree relatives, and 24 patients with major depressive disorder. A high rate of abnormal VF was found in schizophrenic patients and their first-degree relatives, but...
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