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Article

New light on an age-old issue.

Mechanisms of ageing and development - 1 Nov 2008

Whitson Heather E, Pieper Carl F, Cohen Harvey J

Abstract excerpt

In this issue, Varadhan and colleagues propose a methodologic framework that seeks to quantify impaired resiliency in dynamic systems underlying the frailty syndrome. We view this work, which is based on modeling stimulus-response data, as an exciting expansion of longstanding theories of age-related decline in physiologic reserve across systems. We outline ways in which this methodology might make substantial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18926846
DOI: 10.1016/j.mad.2008.09.006
PMCID: PMC2628446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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