Article
Association between CARD15/NOD2 gene polymorphisms and paratuberculosis infection in cattle.
Veterinary microbiology - 2 Mar 2009
Pinedo Pablo J, Buergelt Claus D, Donovan G Art, Melendez Pedro, Morel Laurence, Wu Rongling, Langaee Taimour Y, Rae D Owen
Abstract excerpt
Paratuberculosis represents a major problem in farmed ruminants and at the present is considered a potential zoonosis. The disease is caused by Mycobacterium avium subsp. paratuberculosis, and susceptibility to infection is suspected to have a genetic component. Caspase recruitment domain 15 (CARD15) gene encodes for a cytosolic protein implicated in bacterial recognition during innate immunity. Crohn's disease...
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