Article
Identification of single nucleotide polymorphisms in bovine CARD15 and their associations with health and production traits in Canadian Holsteins.
BMC genomics - 15 Nov 2007
Pant Sameer D, Schenkel Flavio S, Leyva-Baca Ivan, Sharma Bhawani S, Karrow Niel A
Abstract excerpt
BACKGROUND: Toll-like receptor-2 (TLR2) and Caspase Recruitment Domain 15 (CARD15) are important pattern recognition receptors that play a role in the initiation of the inflammatory and subsequent immune response. They have been previously identified as susceptibility loci for inflammatory bowel diseases in humans and are, therefore, suitable candidate genes for inflammatory disease resistance in cattle. The...
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