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Article

Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study.

BMC medicine - 16 Oct 2008

Dehghan Abbas, van Hoek Mandy, Sijbrands Eric J G, Oostra Ben A, Hofman Albert, van Duijn Cornelia M, Witteman Jacqueline C M

Abstract excerpt

BACKGROUND: Recent genome wide association (GWA) studies identified two Single Nucleotide Polymorphisms (SNP) (rs10757278 and rs10757274) in the region of the CDK2NA and CDK2NB genes to be consistently associated with the risks of coronary heart disease (CHD) and myocardial infarction (MI). We examined the SNPs in relation to the risk of CHD and MI in a large population based study of elderly population. METHODS:...

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Identifiers

PMID: 18925945
DOI: 10.1186/1741-7015-6-30
PMCID: PMC2579294

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Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study.PMID 18925945Read ↗

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