Article
Association of CDKN2BAS polymorphism rs4977574 with coronary heart disease: a case-control study and a meta-analysis.
International journal of molecular sciences - 29 Sept 2014
Huang Yi, Ye Huadan, Hong Qingxiao, Xu Xuting, Jiang Danjie, Xu Limin, Dai Dongjun, Sun Jie, Gao Xiang, Duan Shiwei
Abstract excerpt
The goal of our study was to explore the significant association between a non-protein coding single nucleotide polymorphism (SNP) rs4977574 of CDKN2BAS gene and coronary heart disease (CHD). A total of 590 CHD cases and 482 non-CHD controls were involved in the present association study. A strong association of rs4977574 with CHD was observed in females (genotype: p=0.002; allele: p=0.002, odd ratio (OR)=1.57,...
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