Article
Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction.
Electrophoresis - 1 Nov 2008
Dowling Paul, Shields William, Rani Sweta, Meleady Paula, Henry Michael, Jeppesen Per, O'Driscoll Lorraine, Clynes Martin
Abstract excerpt
Media conditioned by dysfunctioning pancreatic beta cells offer an excellent source of potential protein markers associated with this phenotype. Proteins identified from cell culture model systems are often found to be of importance clinically. Previous work by us and others have shown that low-p...
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