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Article

In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae.

The Journal of antimicrobial chemotherapy - 1 Dec 2008

Poudyal Anima, Howden Benjamin P, Bell Jan M, Gao Wei, Owen Roxanne J, Turnidge John D, Nation Roger L, Li Jian

Abstract excerpt

BACKGROUND: Resistance to colistin is emerging in multidrug-resistant Gram-negative bacteria and no solid pharmacodynamic data are available for colistin against Klebsiella pneumoniae. METHODS: Twenty-one multidrug-resistant clinical K. pneumoniae isolates from 16 different clinical sites worldwide were employed. The genetic relatedness of these isolates was examined with PFGE. In vitro pharmacodynamic properties...

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Identifiers

PMID: 18922815
DOI: 10.1093/jac/dkn425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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