Article
[Cloned variants of the L-IVP strain of the vaccinia virus].
Voprosy virusologii - 1 Jan 2000
Petrov V S, Raspopin V V, Pak V N, Urmanov I Kh, Chernyĭ N B, Bachinskiĭ A G
Abstract excerpt
Genomes of vaccinia strain L-IVP and its cloned variants were investigated by restriction and Southern blotting analysis. The strain L-IVP was shown to be heterogeneous and to consist of variants which differed in the genome structure and properties. Clone 1 derived from L-IVP was less reactogeni...
Topics
- Animals
- Blotting, Southern
- Cells, Cultured
- Chick Embryo
- Cloning, Molecular
- Cricetinae
- DNA, Viral
- Genetic Variation
- Genetic Vectors
- Nucleic Acid Hybridization
- Rabbits
- Restriction Mapping
- Serial Passage
- Vaccinia virus
- Virulence
