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Article

Regulation of plaque size and host range by a vaccinia virus gene related to complement system proteins.

Virology - 1 Mar 1991

Takahashi-Nishimaki F, Funahashi S, Miki K, Hashizume S, Sugimoto M

Abstract excerpt

A vaccinia virus variant, LC16m8, and its parental Lister (Elstree) strain (LO) were employed to identify the viral gene(s) responsible for plaque size and host range: the large-plaque-forming LO strain but not the small-plaque-forming LC16m8 strain can actively proliferate in Vero (YTV) cells. Previously, we suggested that some particular gene(s) present in the HindIII D fragment of LO DNA was responsible for...

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PMID: 1994573
DOI: 10.1016/0042-6822(91)90480-y

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