Regulation of plaque size and host range by a vaccinia virus gene related to complement system proteins.

doi:10.1016/0042-6822(91)90480-y

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Article

Regulation of plaque size and host range by a vaccinia virus gene related to complement system proteins.

Virology - 1 Mar 1991

Takahashi-Nishimaki F, Funahashi S, Miki K, Hashizume S, Sugimoto M

Abstract excerpt

A vaccinia virus variant, LC16m8, and its parental Lister (Elstree) strain (LO) were employed to identify the viral gene(s) responsible for plaque size and host range: the large-plaque-forming LO strain but not the small-plaque-forming LC16m8 strain can actively proliferate in Vero (YTV) cells. Previously, we suggested that some particular gene(s) present in the HindIII D fragment of LO DNA was responsible for...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blotting, Southern
Cell Line
DNA, Viral
Gene Expression Regulation, Viral
Genes, Viral
Genetic Complementation Test
Genetic Variation
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open Reading Frames

Recombination, Genetic

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Vaccinia virus

Viral Plaque Assay

Source

Open in PubMed

Identifiers

PMID: 1994573
DOI: 10.1016/0042-6822(91)90480-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1994573-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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