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Article

A molecular footprint of limb loss: sequence variation of the autopodial identity gene Hoxa-13.

Journal of molecular evolution - 1 Dec 2008

Kohlsdorf Tiana, Cummings Michael P, Lynch Vincent J, Stopper Geffrey F, Takahashi Kazuhiko, Wagner Günter P

Abstract excerpt

The homeobox gene Hoxa-13 codes for a transcription factor involved in multiple functions, including body axis and hand/foot development in tetrapods. In this study we investigate whether the loss of one function (e.g., limb loss in snakes) left a molecular footprint in exon 1 of Hoxa-13 that cou...

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Identifiers

PMID: 18855040
DOI: 10.1007/s00239-008-9156-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18855040-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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