A neutral origin for error minimization in the genetic code.

doi:10.1007/s00239-008-9167-4

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Article

A neutral origin for error minimization in the genetic code.

Journal of molecular evolution - 1 Nov 2008

Massey Steven E

Abstract excerpt

The genetic code has the remarkable property of error minimization, whereby the arrangement of amino acids to codons is highly efficient at reducing the deleterious effects of random point mutations and transcriptional and translational errors. Whether this property has been explicitly selected for is unclear. Here, three scenarios of genetic code evolution are examined, and their effects on error minimization...

Topics

Algorithms
Amino Acids
Codon
Evolution, Molecular
Gene Duplication
Genetic Code
Models, Genetic
Mutation
Protein Biosynthesis
RNA, Transfer

Source

Open in PubMed

Identifiers

PMID: 18855039
DOI: 10.1007/s00239-008-9167-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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