Article
A novel transgenic mice model for venous malformation.
Transgenic research - 1 Apr 2009
Wang Yan An, Zheng Jia Wei, Fei Zhao Liang, Jiang Xin Quan, Wang Zhu Gang, Fei Jian, Zhang Zhi Yuan
Abstract excerpt
Vascular anomalies are most commonly seen in the head and neck region, and there is no animal model available of this disease until now. The purpose of this study was to construct a conditional murine polyomavirus middle T antigen gene (PyMT) transgenic mice model, in order to provide a basis for the treatment of vascular anomalies in vivo, as well as the study of PyMT's molecular function. A new conditional...
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