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Article

Gender-dependent effect of ACE I/D and AGT M235T polymorphisms on the progression of urinary albumin excretion in Taiwanese with type 2 diabetes.

American journal of nephrology - 1 Jan 2009

Tien Kai-Jen, Hsiao Jeng-Yueh, Hsu Shih-Chieh, Liang Hui-Ting, Lin Shiu-Ru, Chen Hung-Chun, Hsieh Ming-Chia

Abstract excerpt

BACKGROUND: We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN). METHODS: A total of 525 type 2 diabetics were enrolled to participate in this prospective observational study. ACE and AGT gene polymorphisms were analyzed by polymerase chain reaction. The progression of DN was defined as a shift to a higher stage of DN or a...

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Source

Identifiers

PMID: 18849600
DOI: 10.1159/000163592

Genes

ACE
AGT
DBP

Variants

Provenance

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