Article
Loss of the histone variant H2A.Z restores capping to checkpoint-defective telomeres in Drosophila.
Genetics - 1 Dec 2008
Rong Yikang S
Abstract excerpt
The conserved histone variant H2A.Z fulfills many functions by being an integral part of the nucleosomes placed at specific regions of the genome. Telomeres cap natural ends of chromosomes to prevent their recognition as double-strand breaks. At yeast telomeres, H2A.Z prevents the spreading of si...
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