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Article

Loss of the histone variant H2A.Z restores capping to checkpoint-defective telomeres in Drosophila.

Genetics - 1 Dec 2008

Rong Yikang S

Abstract excerpt

The conserved histone variant H2A.Z fulfills many functions by being an integral part of the nucleosomes placed at specific regions of the genome. Telomeres cap natural ends of chromosomes to prevent their recognition as double-strand breaks. At yeast telomeres, H2A.Z prevents the spreading of silent chromatin into proximal euchromatin. A role for H2A.Z in capping, however, has not been reported in any organism....

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Identifiers

PMID: 18845840
DOI: 10.1534/genetics.108.095547
PMCID: PMC2600928

Genes

ATM
ATR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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