Article
Health risk appraisal models for mass screening of esophageal cancer in Japanese men.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2008
Yokoyama Tetsuji, Yokoyama Akira, Kumagai Yoshiya, Omori Tai, Kato Hoichi, Igaki Hiroyasu, Tsujinaka Toshimasa, Muto Manabu, Yokoyama Masako, Watanabe Hiroshi
Abstract excerpt
BACKGROUND: Because early squamous cell carcinoma (SCC) of the esophagus is detectable by endoscopic esophageal iodine staining with high accuracy and is easily treated by endoscopic mucosectomy, it is important to develop efficient methods for screening candidates for the endoscopic examination. Inactive aldehyde dehydrogenase-2 (ALDH2) is a very strong risk factor for esophageal SCC in alcohol drinkers and thus...
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