Article
Association between glutathione S-transferase A1, M1 and T1 polymorphisms and hypertension.
Pharmacogenetics and genomics - 1 Mar 2008
Oniki Kentaro, Hori Masaharu, Takata Keiji, Yokoyama Tomoko, Mihara Shuichi, Marubayashi Toru, Nakagawa Kazuko
Abstract excerpt
The importance of oxidative stress in hypertension has recently received increasing attention. The association between the incidence of hypertension and a super family of antioxidant enzymes, glutathione S-transferase (GST)A1, GSTM1 and GSTT1, polymorphisms was investigated in 468 Japanese participants in a health screening program. The frequency of the GSTA1*B allele carriers was significantly higher in...
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