Article
HLA class II alleles are not a general susceptibility factor in Guillain-Barré syndrome.
Neurology - 11 Jan 2005
Geleijns K, Schreuder G M Th, Jacobs B C, Sintnicolaas K, van Koningsveld R, Meulstee J, Laman J D, van Doorn P A
Abstract excerpt
OBJECTIVE: To assess whether human leukocyte antigen (HLA)-DRB1 and HLA-DQB1 alleles confer susceptibility to Guillain-Barre syndrome (GBS) or are related to specific clinical or serologic subgroups of GBS. METHODS: The HLA-DRB1 and HLA-DQB1 loci were genotyped by PCR amplification with sequence-specific primers in 164 well-documented Dutch patients with GBS and 207 healthy Dutch control subjects. Patients with...
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