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Article

Identification and functional analysis of antifungal immune response genes in Drosophila.

PLoS pathogens - 3 Oct 2008

Jin Li Hua, Shim Jaewon, Yoon Joon Sun, Kim Byungil, Kim Jihyun, Kim-Ha Jeongsil, Kim Young-Joon

Abstract excerpt

Essential aspects of the innate immune response to microbial infection appear to be conserved between insects and mammals. Although signaling pathways that activate NF-kappaB during innate immune responses to various microorganisms have been studied in detail, regulatory mechanisms that control other immune responses to fungal infection require further investigation. To identify new Drosophila genes involved in...

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Identifiers

PMID: 18833296
DOI: 10.1371/journal.ppat.1000168
PMCID: PMC2542415

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