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Article

Gene expression profiling of liver metastases from colorectal cancer as potential basis for treatment choice

30 Sept 2008

Abstract excerpt

At present no reports on gene expression profiling of liver metastases from colorectal cancer are available. We identified two different signatures using Affymetrix platform: epidermal growth factor receptor pathway was upregulated in metachronous lesions, whereas the pathway mainly related to angiogenesis was in synchronous lesions. Synchronous or metachronous liver metastases could be treated differently on the...

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PMID: 18827815
DOI: 10.1038/sj.bjc.6604681

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