Article
[The relation of asbestosis to human 8-oxoguanine DNA glycosidase polymorphism and DNA damage in peripheral lymphocytes].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Nov 2006
Guo Jun-Xia, Zhao Xiao-Hong, Liu Yong-Quan
Abstract excerpt
OBJECTIVE: To explore the relation of asbestosis to human 8-oxoguanine DNA glycosidase (hOGG1) genotype and DNA damage, the investigation of hOGG1 polymorphism distribution and DNA strand breakages in peripheral lymphocytes was carried on in occupational population. METHODS: A total 101 asbestos-exposed workers and 141 controls were investigated. The DNA damage level was obtained by single cell gel...
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