Article
Novel genetic determinants of low-level aminoglycoside resistance in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy - 1 Dec 2008
Schurek Kristen N, Marr Alexandra K, Taylor Patrick K, Wiegand Irith, Semenec Lucie, Khaira Bhavjinder K, Hancock Robert E W
Abstract excerpt
Pseudomonas aeruginosa strains isolated from patients with persistent lung infections and cystic fibrosis have been found to gradually develop aminoglycoside resistance over time. The aim of this study was to identify potential contributors to low-level aminoglycoside resistance, which may cause such graduated increases in resistance. The Harvard P. aeruginosa PA14 nonredundant library, consisting of...
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