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Analysis of Antibiotic Response in Clinical Wound Pseudomonas aeruginosa Isolates: Unveiling Proteome Dynamics of Tobramycin-Tolerant Phenotype.

Molecular & cellular proteomics : MCP - 1 Dec 2024

Buchholtz Kasandra, Jersie-Christensen Rosa, Krogfelt Karen Angeliki, Mojsoska Biljana

Abstract excerpt

Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic human pathogen, causing serious chronic infections. P. aeruginosa can adapt efficiently to antibiotic stressors via different genotypic or phenotypic strategies such as resistance and tolerance. The adaptation regulatory system is not always very well understood. In this study, we use shotgun proteomics to investigate the system-level response to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39424064
DOI: 10.1016/j.mcpro.2024.100861
PMCID: PMC11617395

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