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Article

Variant between CPT1B and CHKB associated with susceptibility to narcolepsy.

Nature genetics - 1 Nov 2008

Miyagawa Taku, Kawashima Minae, Nishida Nao, Ohashi Jun, Kimura Ryosuke, Fujimoto Akihiro, Shimada Mihoko, Morishita Shinichi, Shigeta Takashi, Lin Ling, Hong Seung-Chul, Faraco Juliette, Shin Yoon-Kyung, Jeong Jong-Hyun, Okazaki Yuji, Tsuji Shoji, Honda Makoto, Honda Yutaka, Mignot Emmanuel, Tokunaga Katsushi

Abstract excerpt

Narcolepsy (hypocretin deficiency), a sleep disorder characterized by sleepiness, cataplexy and rapid eye movement (REM) sleep abnormalities, is tightly associated with HLA-DRB1*1501 (M17378) and HLA-DQB1*0602 (M20432). Susceptibility genes other than those in the HLA region are also likely invol...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 18820697
DOI: 10.1038/ng.231

Genes

CHKB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18820697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Variant between CPT1B and CHKB associated with susceptibility to narcolepsy.PMID 18820697Read ↗

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