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Genome structure and transcriptional regulation of human coronavirus NL63

17 Nov 2004

Abstract excerpt

BACKGROUND: Two human coronaviruses are known since the 1960s: HCoV-229E and HCoV-OC43. SARS-CoV was discovered in the early spring of 2003, followed by the identification of HCoV-NL63, the fourth member of the coronaviridae family that infects humans. In this study, we describe the genome structure and the transcription strategy of HCoV-NL63 by experimental analysis of the viral subgenomic mRNAs. RESULTS: The...

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PMID: 15548333
DOI: 10.1186/1743-422x-1-7

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