Article
Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination.
The Journal of general virology - 1 Nov 2012
Dominguez Samuel R, Sims Gregory E, Wentworth David E, Halpin Rebecca A, Robinson Christine C, Town Christopher D, Holmes Kathryn V
Abstract excerpt
This study compared the complete genome sequences of 16 NL63 strain human coronaviruses (hCoVs) from respiratory specimens of paediatric patients with respiratory disease in Colorado, USA, and characterized the epidemiology and clinical characteristics associated with circulating NL63 viruses over a 3-year period. From 1 January 2009 to 31 December 2011, 92 of 9380 respiratory specimens were found to be positive...
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