Article
Association analysis of SCN9A gene variants with borderline personality disorder.
Journal of psychiatric research - 1 Dec 2008
Tadić André, Baskaya Omur, Victor Anja, Lieb Klaus, Höppner Wolfgang, Dahmen Norbert
Abstract excerpt
Borderline personality disorder (BPD) is a serious psychiatric disorder affecting about 1-2% of the general population. Key features of BPD are emotional instability, strong impulsivity, repeated self-injurious behavior (SIB) and dissociation. In the etiology of BPD and its predominant symptoms, genetic factors have been suggested. The voltage-gated sodium channel Nav1.7 is expressed in sensory neurons and in the...
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