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Article

Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway.

Molecular and cellular biology - 1 Dec 2008

Mizuno Tomoaki, Fujiki Kota, Sasakawa Aya, Hisamoto Naoki, Matsumoto Kunihiro

Abstract excerpt

Mitogen-activated protein kinases (MAPKs) are integral to the mechanisms by which cells respond to physiological stimuli and a wide variety of environmental stresses. In Caenorhabditis elegans, the stress response is controlled by a c-Jun N-terminal kinase (JNK)-like mitogen-activated protein kinase (MAPK) signaling pathway, which is regulated by MLK-1 MAPK kinase kinase (MAPKKK), MEK-1 MAPK kinase (MAPKK), and...

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Identifiers

PMID: 18809575
DOI: 10.1128/MCB.00938-08
PMCID: PMC2593375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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