Article
Genetic analysis of the clusterin gene in pseudoexfoliation syndrome.
Molecular vision - 22 Sept 2008
Burdon Kathryn P, Sharma Shiwani, Hewitt Alex W, McMellon Amy E, Wang Jie Jin, Mackey David A, Mitchell Paul, Craig Jamie E
Abstract excerpt
PURPOSE: Pseudoexfoliation syndrome is a major risk factor for the development of glaucoma. Following recent reports of a strong association of coding variants in the lysyl oxidase-like 1 (LOXL1) gene with this syndrome but low penetrance and variable disease frequency between different populations, we aimed to identify additional genetic factors contributing to the disease. The clusterin (CLU) gene has been...
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