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Article

Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.

Experimental eye research - 1 Oct 2014

Padhy Biswajit, Nanda Gargi G, Chowdhury Mahasweta, Padhi Debanand, Rao Aparna, Alone Debasmita P

Abstract excerpt

Pseudoexfoliation (PEX), an age related disorder is a prominent contributor to secondary glaucoma. Earlier studies have suggested involvement of clusterin in the development of PEX. We designed a case-control study to understand the role of clusterin single nucleotide polymorphisms (SNPs) in PEX and analyzed the role of risk alleles in the disease. Genotyping of SNPs in 136 PEX patients and 89 controls of Indian...

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Identifiers

PMID: 25057782
DOI: 10.1016/j.exer.2014.07.005

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