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Identification of a human subcortical maternal complex

26 Dec 2014

Abstract excerpt

Maternal effect genes play essential roles in early embryonic development. However, the mechanisms by which maternal effect genes regulate mammalian early embryonic development remain largely unknown. Recently, we identified a subcortical maternal complex (SCMC) that is composed of at least four proteins encoded by Mater, Floped, Tle6 and Filia and is critical for mouse preimplantation development. The present...

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PMID: 25542835
DOI: 10.1093/molehr/gau116

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