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Article

The influence of two variants in the adenosine triphosphate-binding cassette transporter 1 gene on plasma lipids and carotid atherosclerosis.

Metabolism: clinical and experimental - 1 Oct 2008

Sandhofer Anton, Iglseder Bernhard, Kaser Susanne, Morè Elena, Paulweber Bernhard, Patsch Josef R

Abstract excerpt

Variants in the adenosine triphosphate-binding-cassette transporter 1 (ABCA1) gene are known to affect high-density lipoprotein cholesterol and plasma triglycerides and the development of atherosclerosis. We investigated the influence of the R219K and I883M variants in the ABCA1 gene on plasma lipids and carotid intima media thickness and plaque extent in 688 healthy men (40-60 years old). The R219K variant...

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Source

Identifiers

PMID: 18803945
DOI: 10.1016/j.metabol.2008.05.009

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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