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Article

Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1.

Biochemical and biophysical research communications - 21 Nov 2008

Yu Xi-Yong, Song Yao-Hua, Geng Yong-Jian, Lin Qiu-Xiong, Shan Zhi-Xin, Lin Shu-Guang, Li Yangxin

Abstract excerpt

Glucose toxicity is an important initiator of cardiovascular disease, contributing to the development of cardiomyocyte death and diabetic complications. The present study investigated whether high glucose state could induce apoptosis of rat cardiomyocyte cell line H9C2 through microRNA regulated...

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Identifiers

PMID: 18801338
DOI: 10.1016/j.bbrc.2008.09.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18801338-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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