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Article

miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts

19 Sept 2014

Abstract excerpt

BACKGROUND: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling due to ER stress is associated with the development of myocardial infarction (MI). MicroRNAs (miRNAs) are key regulators of cardiovascular development and deregulation of miRNA expression is...

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Share to Autophagy in Disease and Therapy
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PMID: 25302112
DOI: 10.1186/2045-3701-4-56

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