Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.

Psychiatric genetics - 1 Oct 2008

Wray Naomi R, James Michael R, Handoko Herlina Y, Dumenil Troy, Lind Penelope A, Montgomery Grant W, Martin Nicholas G

Abstract excerpt

OBJECTIVES: Association of the valine/methionine variant at codon 66 (Val66Met) of brain derived neurotrophic factor (BDNF) has been reported inconsistently across a spectrum of psychiatric disorders. Haplotypes of six tagging single nucleotide polymorphisms (SNPs) of a 37-kb region of dystrobrevin-binding protein 1 (DTNBP1) were found to be associated with schizophrenia. These haplotypes have not been studied...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Depression

Share to Dystrophin-Associated Proteins

Share to Linkage Disequilibrium

Share to Neuropeptides

Share to Neurotic Disorders

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 18797396
DOI: 10.1097/YPG.0b013e3283050aee

Genes

DTNBP1
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.PMID 18797396Read ↗

A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression.Semantic proximity Read ↗

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.Semantic proximity Read ↗

Association study of candidate variants of COMT with neuroticism, anxiety and depression.Semantic proximity Read ↗

Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder.Semantic proximity Read ↗

Brain derived neurotrophic factor (BDNF) Val66Met polymorphism is not risk factor for bipolar disorderSemantic proximity Read ↗

Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.Semantic proximity Read ↗

Association study between the serotonin 1A receptor (HTR1A) gene and neuroticism, major depression, and anxiety disorders.Semantic proximity Read ↗

BDNF polymorphisms across the spectrum of psychiatric morbidity: A protocol for a systematic review and meta-analysis.Semantic proximity Read ↗

Role of BDNF in bipolar and unipolar disorder: clinical and theoretical implications.Semantic proximity Read ↗

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.