Article
Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease.
Cytokine - 1 Oct 2008
Sookoian Silvia, Castaño Gustavo, Gianotti Tomas Fernández, Gemma Carolina, Rosselli María Soledad, Pirola Carlos Jose
Abstract excerpt
AIMS: To investigate the role of gene variants and derived haplotypes of the STAT3 transcription factor in nonalcoholic fatty liver disease (NAFLD) and their relation with the clinical disease severity. PATIENTS AND METHODS: 108 patients with NAFLD and different stages of clinical disease severity, and a group of 55 healthy individuals were included in a Hospital-based study. We selected 3 tagSNPs showing a minor...
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