Article
Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines.
BMC cancer - 14 Sept 2008
Smith Danielle J, Cossins Luke R, Hatzinisiriou Irene, Haber Michelle, Nagley Phillip
Abstract excerpt
BACKGROUND: Many cancers preferentially meet their energy requirements through the glycolytic pathway rather than via the more efficient oxidative phosphorylation pathway. It is thought that this is an important adaptation in cancer malignancy. We investigated whether use of glycolysis for energy production even in the presence of oxygen (known as the Warburg effect) varied between neuroblastoma cell lines with...
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