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Article

The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides.

BMC medical genetics - 12 Sept 2008

Dallongeville Jean, Cottel Dominique, Wagner Aline, Ducimetière Pierre, Ruidavets Jean-Bernard, Arveiler Dominique, Bingham Annie, Ferrières Jean, Amouyel Philippe, Meirhaeghe Aline

Abstract excerpt

BACKGROUND: The goal of the present study was to assess the effect of genetic variability at the APOA5/A4/C3/A1 cluster locus on the risk of metabolic syndrome. METHODS: The APOA5 Ser19Trp, APOA5 -12,238T>C, APOA4 Thr347Ser, APOC3 -482C>T and APOC3 3238C>G (SstI) polymorphisms were analyzed in a representative population sample of 3138 men and women from France, including 932 individuals with metabolic syndrome...

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Source

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Identifiers

PMID: 18789138
DOI: 10.1186/1471-2350-9-84
PMCID: PMC2551592

Genes

APOA5
APOA4
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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