Article
Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men.
International journal of cardiology - 13 Jan 2006
Dallongeville Jean, Cottel Dominique, Montaye Michèle, Codron Valérie, Amouyel Philippe, Helbecque Nicole
Abstract excerpt
OBJECTIVE: The goal of the present study was to assess the impact of 4 single nucleotide polymorphisms (SNPs) of APOA5/A4/C3 gene cluster on lipid levels and coronary heart disease (CHD) risk in French men. METHODS: A total of 442 men with CHD were recruited from the university hospital and compared to 475 men free of CHD from the population of the same geographical area. The APOA5 S19W, APOA5 -l2,238T>C, APOA4...
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