Article
Role of nitric oxide in P. aeruginosa keratitis caused by distinct bacterial phenotypes.
Eye & contact lens - 1 Jul 2008
Wang Wen, Xue Meilang, Willcox Mark, Thakur Archana
Abstract excerpt
OBJECTIVES: Nitric oxide (NO) plays an important role as a signal molecule as well as a cytotoxic effector molecule of the nonspecific innate immune response. The aim of this study was to examine the role played by NO during P. aeruginosa keratitis. METHODS: In this study, we investigated the level of NO in BALB/c mouse eyes challenged with P. aeruginosa strains Pear1 (noninvasive/noncytotoxic), 6294 (invasive)...
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