Article
Ca2+-dependent metarhodopsin inactivation mediated by calmodulin and NINAC myosin III.
Neuron - 11 Sept 2008
Liu Che-Hsiung, Satoh Akiko K, Postma Marten, Huang Jiehong, Ready Donald F, Hardie Roger C
Abstract excerpt
Phototransduction in flies is the fastest known G protein-coupled signaling cascade, but how this performance is achieved remains unclear. Here, we investigate the mechanism and role of rhodopsin inactivation. We determined the lifetime of activated rhodopsin (metarhodopsin = M( *)) in whole-cell recordings from Drosophila photoreceptors by measuring the time window within which inactivating M( *) by...
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